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Avapro (Irbesartan)Irbesartan (trade names include Avapro; Aprovel; CO Irbesartan; Irbesartan Mylan; Iretensa; Sandoz Irbesartan; Irovel; Teva-Irbesartan; Karvea) is an antihypertensive drug from angiotensin II antagonists pharmacological group. This medication is powerfully efficient for the treatment of hypertension (high blood pressure) and diabetic nephropathy (kidney disease caused by diabetes type 2). It works by blocking the action of certain chemicals that tighten the blood vessels, so blood flows more smoothly. Irbesartan may be used alone or in combination with other medicines, such as hydrochlorothiazide.

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  • Type of Irbesartan - brand / generic:
  • Avapro (Irbesartan) generic
  • Irbesartan (Avapro) generic
  • Avapro generic
  • Aprovel generic
  • Irovel brand
  • Irovel (Irbesartan) brand
  • Avapro generic
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    There is an additional general information about Irbesartan (Avapro, Aprovel, Karvea):

    Medical and pharmaceutical categories for irbesartan:

  • Angiotensin II receptor antagonists
  • Antihypertensive medications
  • Medicines for the treatment of nephropathy in type 2 diabetic patients


    The Anatomical Therapeutic Chemical (ATC) classification system irbesartan codes:

  • C - Cardiovascular system
  • C09 - Agents acting on the renin-angiotensin system
  • C09C - Angiotensin II antagonists, plain
  • C09CA - Angiotensin II antagonists, plain
  • C09CA04 - Irbesartan

  • C09D - Angiotensin II antagonists, combinations
  • C09DA - Angiotensin II antagonists and diuretics
  • C09DA04 - Irbesartan and diuretics

  • C09DB - Angiotensin II antagonists and calcium channel blockers
  • C09DB05 - Irbesartan and Amlodipine


    Irbesartan in The International Statistical Classification of Diseases and Related Health Problems (ICD-10, World Health Organization) codes:

  • Type 2 diabetes mellitus - E11
  • Essential (primary) hypertension - I10
  • Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions - N14


    Pregnancy categories for Irbesartan (Aprovel, Avapro):

  • D - Australia
  • D - United States (Positive evidence of risk)


    Salts and other irbesartan forms used as active pharmaceutical ingredients (API):

  • Irbesartan Base


    Synonyms of irbesartan, international and chemical names:

  • Irbesarran
  • Irbesartane
  • Irbesartanum
  • Irbezartan
  • Irbisartan


    Best known irbesartan brands, generics and and trade names in various countries:

  • Aprovel - Sanofi-Aventis; Bristol-Myers Squibb; Chinoin; Lek
  • Avapro - Bristol-Myers Squibb; Sanofi-Aventis
  • CO Irbesartan - Cobalt Pharmaceuticals
  • Fritens - Kalbe Farma
  • Irbesartan - Apotex; Cipla; Mylan; Pro Doc; Sandoz; Stada; Teva
  • Irbetan - Boston Pharma
  • Iretensa - Fahrenheit
  • Irovel - Sun Pharmaceutical Industries
  • Irtan - Ikapharmindo Putramas
  • Irvask - Kalbe Farma
  • Irvell - Novell Pharmaceutical Laboratories
  • Karvea - Bristol-Myers Squibb; Sanofi-Aventis
  • PMS-Irbesartan - Pharmascience
  • Ratio-Irbesartan - Ratiopharm; Teva
  • Sandoz Irbesartan - Sandoz


    Pharmaceutical active ingredients used in medicine in combinations with irbesartan:

  • Amlodipine
  • Hydrochlorothiazide


    Some other medications in Avapro and Aprovel (Irbesartan) pharmacological classes:

  • Adalat (Nifedipine)
  • Altace (Ramipril)
  • Atacand (Candesartan)
  • Avalide (Hydrochlorothiazide; Irbesartan)
  • Benicar (Olmesartan)
  • Benicar HCT (Hydrochlorothiazide; Olmesartan)
  • Calan (Verapamil)
  • Cardizem (Diltiazem)
  • Cozaar (Losartan)
  • Diovan (Valsartan)
  • Diovan HCT (Hydrochlorothiazide; Valsartan)
  • Edarbi (Azilsartan)
  • Hytrin (Terazosin)
  • Hyzaar (Hydrochlorothiazide; Losartan)
  • Inderal (Propranolol)
  • Lopressor; Toprol XL (Metoprolol)
  • Lozol (Indapamide)
  • Micardis (Telmisartan)
  • Micardis HCT (Hydrochlorothiazide; Telmisartan)
  • Normodyne (Labetalol)
  • Norvasc (Amlodipine)
  • Plendil (Felodipine)
  • Tenormin (Atenolol)
  • Teveten (Eprosartan)
  • Vasotec (Enalapril)
  • Verdia (Tasosartan)
  • Zebeta (Bisoprolol)


    IRBESARTAN (AVAPRO, APROVEL) MEDICATION GUIDE

    What is Irbesartan, generic Avapro and Aprovel?

    Irbesartan is in a class of drugs called angiotensin II receptor antagonists. This medication prevents the constriction (narrowing) of blood vessels (veins and arteries).
    Irbesartan is used to treat high blood pressure (hypertension) and diabetic nephropathy (kidney disease caused by diabetes).
    This medicine may also be used for purposes other than those listed in this medication guide.


    How does Irbesartan work?

    The important action of Angiotensin II enzyme is vasoconstriction produced by increasing adrenaline or noradrenaline release and by increasing sympathetic outflow. Angiotensin II causes vasoconstriction and it prevents the secretion of aldosterone. Aldosterone causes an increase in blood volume. Irbesartan is and Angiotensin II receptor antagonist, which decreases blood volume and cause vasodilation as a result of which the blood pressure is reduced.


    Irbesartan (Avapro, Aprovel) indications and usage

    Hypertension

    Avapro (Irbesartan) is indicated for the treatment of hypertension. This medication may be used alone or in combination with other antihypertensive agents.

    Nephropathy in type 2 diabetic patients

    Irbesartan is indicated for the treatment of diabetic nephropathy with an elevated serum creatinine and proteinuria (>300 mg / day) in patients with hypertension and type 2 diabetes. In this population, irbesartan reduces the rate of progression of nephropathy as measured by the occurrence of doubling of serum creatinine or end-stage renal disease (need for dialysis or renal transplantation).


    Side effects of Irbesartan

    The possible side effects reported with this drug during clinical trials and in post marketing are chills, fever, facial edema, hypertension, flushing, myocardial infarction, heart failure, angina pectoris, hypertensive crisis, dermatitis, pruritis, sexual dysfunction, constipation, change in libido, flatulence, sleep disturbance, muscle cramp, abnormal urination, vision disturbance, pulmonary congestion.


    Guidelines before taking Irbesartan (Avapro) generic

  • Before using irbesartan, tell your doctor if you have kidney disease; liver disease; are on a salt-restricted diet or have high levels of potassium in your blood; are taking a potassium supplements, or a potassium-sparing diuretic such as amiloride, triamterene or spironolactone.
  • This medication is in the FDA pregnancy category D. This means that it is known to be harmful to an unborn baby. When used during the second and third trimesters of pregnancy, irbesartan can cause injury and even death to the developing fetus. Do not take Avapro generic if you are pregnant or could become pregnant during treatment.
  • It is not known whether irbesartan passes into breast milk. Do not take generic Avapro without first talking to your doctor if you are breast-feeding a baby.


    What are the common dosages of Irbesartan?

    The recommended starting dosage of irbesartan is 150 mg once daily, administered with or without food. The dose can be slowly increased to a maximum of 300 mg / day. The effectiveness of the treatment can be added by incluing an hydrochlorthiazide diruetic in the treatment. The recommended dose for diabetic nephropathy is 300 mg once daily.


    What may interact with Irbesartan?

  • blood pressure medicines
  • antiinflammatory pain medications such as ibuprofen
  • bosentan
  • imatinib
  • delavirdine
  • fluconazole
  • lithium containing drugs
  • hawthorn
  • monoamine oxidase inhibitors
  • rifampin
  • potassium salts or potassium supplements
  • water pills (especially potassium-sparing diuretics)
  • voriconazole


    Where should I keep Irbesartan pills?

    Store irbesartan at 77 degrees F (25 degrees C). Brief storage at room temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Keep Avapro generic out of the reach of children and away from pets.


    What happens if I overdose?

    Seek emergency medical attention. Symptoms of overdose with irbesartan are not well known, but might include weakness, dizziness, fainting, chest pain and fatigue.


    What is the difference between brand and generic Irbesartan (Avapro)?

    Brand and generic Avapro and other trade names contains irbesartan as the main active ingredient and hence there is no significant difference between the two. The mechanism of action and the effectiveness remain the same in both Avapro brand and generic. The difference between brand and generic forms are packaging, pricing and the brand name. You can buy cheap Avapro online when it is sold as a generic drug.


    Where and how to buy Avapro / Irbesartan generic online?

    You can buy Avapro, order or purchase irbesartan medicine online from one of trusted online pharmacy, the list and review of which you can find above on this webpage. When you order irbesartan drug online from this qualitative drugstores, it will reach your doorstep without any hassles. You can also save more when you buy irbesartan online in more numbers with the volume discounts these pharma shops offer.


    Why is the price of Irbesartan (Generic Avapro) so cheap on "Discount Meds", "Drugs for Health", "Generic Doctor" and "Cheap Meds for Sale" online pharmacies?

    This certified online pharmacies sells generic irbesartan, which is priced lesser compared to brands because of the savings in research and development of the drug. Generic drugs do not require any spending on research and development activities. They also source all drugs directly from the manufacturers and hence able to negotiate better prices on bulk orders.


    Here is a list of some medications containing "Irbesartan" as a main active pharmaceutical ingredient (API) of irbesartan drugs, their trade names, available forms, doses and also pharmaceutical companies - manufacturers, distributors and suppliers, researchers and developers:

    Trade name of the drug Pharmaceutical forms and doses Companies
    Aprovel
  • Tablets, Film-Coated; Oral; Irbesartan 150 mg
  • Tablets, Film-Coated; Oral; Irbesartan 300 mg
  • Tablets, Film-Coated; Oral; Irbesartan 75 mg
  • Tablets; Oral; Irbesartan 150 mg
  • Tablets; Oral; Irbesartan 300 mg
  • Tablets; Oral; Irbesartan 75 mg
  • Sanofi-Aventis
  • Bristol-Myers Squibb
  • Chinoin
  • DKSH
  • IDS Group
  • Lek
  • Metro Drug Distribution
  • The Glory Medicina
  • Zuellig Pharma
  • Avapro
  • Tablets; Oral; Irbesartan 150 mg
  • Tablets; Oral; Irbesartan 300 mg
  • Tablets; Oral; Irbesartan 75 mg
  • Bristol-Myers Squibb
  • Sanofi-Aventis
  • Irbesartan
  • Tablets; Oral; Irbesartan 75 mg
  • Tablets; Oral; Irbesartan 150 mg
  • Tablets; Oral; Irbesartan 300 mg
  • Mylan
  • Irovel
  • Tablets; Oral; Irbesartan 150 mg
  • Tablets; Oral; Irbesartan 300 mg
  • Sun Pharmaceutical Industries
  • Karvea
  • Tablets; Oral; Irbesartan 150 mg
  • Tablets; Oral; Irbesartan 300 mg
  • Tablets; Oral; Irbesartan 75 mg
  • Bristol-Myers Squibb
  • Sanofi-Aventis
  • PMS-Irbesartan
  • Tablets; Oral; Irbesartan 150 mg
  • Tablets; Oral; Irbesartan 300 mg
  • Tablets; Oral; Irbesartan 75 mg
  • Pharmascience
  • Medicell Pharmaceutical
  • Tada Pharma
  • Sandoz Irbesartan
  • Tablets; Oral; Irbesartan 150 mg
  • Tablets; Oral; Irbesartan 300 mg
  • Tablets; Oral; Irbesartan 75 mg
  • Sandoz
  • Teva-Irbesartan
  • Tablets; Oral; Irbesartan 150 mg
  • Tablets; Oral; Irbesartan 300 mg
  • Tablets; Oral; Irbesartan 75 mg
  • Teva


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